Ampanefena is a town and commune (Malagasy: kaominina) in northern Madagascar. It belongs to the district of Vohemar, which is a part of Sava Region. In 2008 its population was estimated to 23.000. Primary and junior level secondary education are available in town. The majority 98% of the population of the commune are farmers, while an additional 1% receives their livelihood from raising livestock. The most important crop is vanilla, while other important products are coffee and rice. Industry and services provide both employment for 0.5% of the population.