Androgen insensitivity syndrome (AIS) is an intersex condition with an estimated prevalence of about 1:20,000-64,000 in XY (chromosomally male) births, resulting in the partial or complete inability of the cell to respond to androgens.The unresponsiveness of the cell to the presence of androgenic hormones can impair or prevent the masculinization of male genitalia in the developing fetus, as well as impairing or preventing the development of male secondary sexual characteristics at puberty, but does not significantly impair female genital or sexual development. As such, the insensitivity to androgens is clinically significant only when it occurs in genetic males (i.e. individuals with a Y-chromosome, or more specifically, an SRY gene). Clinical phenotypes in these individuals range from a