Antibody-dependent enhancement
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. ADE may cause enhanced respiratory disease and acute lung injury after respiratory virus infection (ERD) with symptoms of monocytic infiltration and an excess of eosinophils in respiratory tract. ADE along with type 2 T helper cell-dependent mechanisms may contribute to a development of the vaccine associated disease enhancement (VADE), which is not limited to respiratory disease. Some vaccine candidates that targeted coronaviruses, RSV virus and Dengue virus elicited VADE, and were terminated from further development or became approved for use on
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AdeAntibody dependent enhancementCOVID-19 misinformationDengue_feverDengue fever outbreaksDengue vaccineDengue virusDisease enhancementEnhancementEnhancing antibodyFc receptorHistory of COVID-19 vaccine developmentImmune enhancementImmunological memoryIndex of immunology articlesInfluenza A virus subtype H7N9List of MeSH codes (G04)List of acronyms: AMalik PeirisMoi Meng LingNeutralizing antibodyOriginal antigenic sinScott HalsteadVaccine-enhanced infectionViral hemorrhagic feverZika virus vaccine
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Antibody-dependent enhancement
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. ADE may cause enhanced respiratory disease and acute lung injury after respiratory virus infection (ERD) with symptoms of monocytic infiltration and an excess of eosinophils in respiratory tract. ADE along with type 2 T helper cell-dependent mechanisms may contribute to a development of the vaccine associated disease enhancement (VADE), which is not limited to respiratory disease. Some vaccine candidates that targeted coronaviruses, RSV virus and Dengue virus elicited VADE, and were terminated from further development or became approved for use on
has abstract
Als infektionsverstärkende Ant ...... r Entwicklung von Impfstoffen.
@de
Antibody-dependent enhancement ...... have had those viruses before.
@en
Il potenziamento anticorpo-dip ...... lta anche la sua replicazione.
@it
La facilitation de l'infection ...... ovoquaient une telle réaction.
@fr
La potenciació de la infecció ...... in tingut aquests virus abans.
@ca
Антителозависимое усиление инф ...... яжелое протекание заболевания.
@ru
التعزيز المعتمد على الأجسام ال ...... أصيبوا بهذه الفيروسات من قبل.
@ar
抗体依存性感染増強 (Antibody-dependent ...... 作用は、免疫細胞によるウイルス抗体複合体の食作用を促進する。
@ja
抗体依赖增强作用(英語:Antibody-dependent ...... 进病毒在体内的复制,恶化疾病的严重度或诱发更严重的额外徵候。
@zh
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Als infektionsverstärkende Ant ...... r Entwicklung von Impfstoffen.
@de
Antibody-dependent enhancement ...... or became approved for use on
@en
Il potenziamento anticorpo-dip ...... lta anche la sua replicazione.
@it
La facilitation de l'infection ...... es cellules immunocompétentes.
@fr
La potenciació de la infecció ...... Normalment, el procés de fagoc
@ca
Антителозависимое усиление инф ...... яжелое протекание заболевания.
@ru
التعزيز المعتمد على الأجسام ال ...... ، إذ سيؤدي ذلك إلى تكاثر الفير
@ar
抗体依存性感染増強 (Antibody-dependent ...... 作用は、免疫細胞によるウイルス抗体複合体の食作用を促進する。
@ja
抗体依赖增强作用(英語:Antibody-dependent ...... 进病毒在体内的复制,恶化疾病的严重度或诱发更严重的额外徵候。
@zh
label
Antibody-dependent enhancement
@en
Facilitation de l'infection par des anticorps
@fr
Infektionsverstärkende Antikörper
@de
Potenciació per anticossos de la infecció
@ca
Potenziamento anticorpo-dipendente
@it
Антителозависимое усиление инфекции
@ru
تعزيز معتمد على الجسم المضاد
@ar
抗体依存性感染増強
@ja
抗体依赖的增强作用
@zh