Apatinib
Apatinib, also known as Rivoceranib, is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR). It is an orally bioavailable, small molecule agent which is thought to inhibit angiogenesis in cancer cells; specifically apatinib inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. This agent also mildly inhibits c-Kit and c-SRC tyrosine kinases.
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Apatinib
Apatinib, also known as Rivoceranib, is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR). It is an orally bioavailable, small molecule agent which is thought to inhibit angiogenesis in cancer cells; specifically apatinib inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. This agent also mildly inhibits c-Kit and c-SRC tyrosine kinases.
has abstract
Apatinib, also known as Rivoce ...... nced hepatocellular carcinoma.
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CAS number
811803-05-1
DrugBank
FDA UNII code
5S371K6132
PubChem
Wikipage page ID
24,682,338
page length (characters) of wiki page
Wikipage revision ID
1,022,088,699
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ATC prefix
none
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CAS number
ChemSpiderID
DrugBank
DB14765
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IUPAC name
N--2-nicotinamide
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PubChem
11,315,474
routes of administration
Oral
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SMILES
C1CCCC2=CC=CNCC3=CNCC4=CC=NC=C4
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StdInChIKey
WPEWQEMJFLWMLV-UHFFFAOYSA-N
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synonyms
Rivoceranib; YN968D1
@en
verifiedrevid
459,713,760
wikiPageUsesTemplate
hypernym
comment
Apatinib, also known as Rivoce ...... it and c-SRC tyrosine kinases.
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label
Apatinib
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