The Apostolic Vicariate of Pakse (Latin: Vicariatus Apostolicus Paksensis) is a Latin rite missionary territorial jurisdiction of the Catholic Church in Laos. As an apostolic vicariate, it is a pre-diocesan jurisdiction, entitled to a titular bishop. It covers southern Laos. It is exempt, i.e., not part of any ecclesiastical province but directly dependent on the Holy See and notably its missionary Roman Congregation for the Evangelization of Peoples. Its cathedral episcopal see is Cathedral of the Sacred Heart, in Pakse.