Burgess Brook is a tributary of North Branch Mehoopany Creek in Wyoming County, Pennsylvania, in the United States. It is approximately 1.2 miles (1.9 km) long and flows through North Branch Township. The watershed of the stream has an area of 1.42 square miles (3.7 km2). The stream is narrow, with a high gradient, and is located in a remote area, mostly far away from any roads. It is designated as Class A Wild Trout Waters and has a large population of brook trout, as well as smaller numbers of brown trout. Three other fish species are also present in the stream.