CD58
CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to.
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Alan M. KrenskyAlefaceptAntigens, cd58Artificial antigen presenting cellsCD2Cd58Erythrocyte rosettingFollicular lymphomaImmunoglobulin superfamilyLFA-3List of MeSH codes (D12.776.395)List of MeSH codes (D12.776.543)List of MeSH codes (D23)List of human clusters of differentiationList of human protein-coding genes 1Lymphocyte function-associated antigenOutline of immunologyProstvac
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CD58
CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to.
has abstract
CD58, or lymphocyte function-a ...... ssical Hodgkin lymphoma (cHL).
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chromosome
EntrezGene
HGNCid
OMIM id
RefSeq
UniProt
Wikipage page ID
10,872,588
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Wikipage revision ID
1,011,263,351
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AltSymbols
LFA3
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Arm
p
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Chromosome
EntrezGene
HGNCid
name
CD58 molecule
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OMIM
RefSeq
NM_001779
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symbol
CD58
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UniProt
P19256
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wikiPageUsesTemplate
subject
hypernym
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CD58, or lymphocyte function-a ...... ell receptors are reactive to.
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label
CD58
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isPrimaryTopicOf
name
CD58 molecule
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