CDKN2A
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed in many tissues and cell types. The gene codes for two proteins, including the INK4 family member p16 (or p16INK4a) and p14arf. Both act as tumor suppressors by regulating the cell cycle. p16 inhibits cyclin dependent kinases 4 and 6 (CDK4 and CDK6) and thereby activates the retinoblastoma (Rb) family of proteins, which block traversal from G1 to S-phase. p14ARF (known as p19ARF in the mouse) activates the p53 tumor suppressor. Somatic mutations of CDKN2A are common in the majority of human cancers, with estimates that CDKN2A is the second most commonly inactivated gene in cancer after p53. Germline mutations of CDKN2A are associated wit
Acute lymphoblastic leukemiaAdenocarcinoma of the lungAdenomatoid tumorAdrenocortical carcinomaAntisense RNACCDC180CDKN2DCancer epigeneticsChordomaCyclin-dependent kinase inhibitor 2ACyclin dependent kinase inhibitor 2ADysplastic nevus syndromeEnteropathy-associated T-cell lymphomaEpitranscriptomeFollicular lymphomaHPV-positive oropharyngeal cancerIn situ lymphoid neoplasiaJun dimerization proteinList of human protein-coding genes 1Li–Fraumeni syndromeMelanomaMonomorphic epitheliotropic intestinal T cell lymphomaMyocardial_infarctionP16Pancreatic cancerPapillary renal cell carcinomaPharmacoepigeneticsPrimary cutaneous diffuse large B-cell lymphoma, leg typePrimary testicular diffuse large B-cell lymphomaRonald DePinhoSTK35L1Sex-linked barringSquamous-cell carcinoma of the lungT-Cell Acute Lymphoblastic LeukemiaVero cellZBTB48
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CDKN2A
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed in many tissues and cell types. The gene codes for two proteins, including the INK4 family member p16 (or p16INK4a) and p14arf. Both act as tumor suppressors by regulating the cell cycle. p16 inhibits cyclin dependent kinases 4 and 6 (CDK4 and CDK6) and thereby activates the retinoblastoma (Rb) family of proteins, which block traversal from G1 to S-phase. p14ARF (known as p19ARF in the mouse) activates the p53 tumor suppressor. Somatic mutations of CDKN2A are common in the majority of human cancers, with estimates that CDKN2A is the second most commonly inactivated gene in cancer after p53. Germline mutations of CDKN2A are associated wit
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CDKN2A (англ. Cyclin dependent ...... алізований у цитоплазмі, ядрі.
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CDKN2A, also known as cyclin-d ...... sk of coronary artery disease.
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CDKN2A (англ. Cyclin dependent ...... : ВалінW: Триптофан Y: Тирозин
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CDKN2A, also known as cyclin-d ...... s of CDKN2A are associated wit
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CDKN2A
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CDKN2A
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