CHEK2
CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase. CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in response to DNA damage. Mutations to the CHEK2 gene have been linked to a wide range of cancers.
ATG5ATM serine/threonine kinaseAutophosphorylationBRCA1BRCA mutationCHEK1CHEK2 (gene)CHK2CHK2 checkpoint homologCds1Checkpoint kinaseChek2Chk2Chromosome 22DNA-SCARSDNA damage (naturally occurring)GINS2Hereditary breast–ovarian cancer syndromeIn situ lymphoid neoplasiaKadmon CorporationLFS2Lfs2List of OMIM disorder codesList of human protein-coding genes 1Li–Fraumeni syndromeMDC1MSH2MUS81Mcr1Meiotic recombination checkpointMichael StrattonMinute virus of miceOvarian cancer1,2-dimethoxyethaanPER1PLK1PLK3PrexasertibPromyelocytic leukemia proteinProtein kinase domain
Link from a Wikipage to another Wikipage
primaryTopic
CHEK2
CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase. CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in response to DNA damage. Mutations to the CHEK2 gene have been linked to a wide range of cancers.
has abstract
CHEK2 (Checkpoint kinase 2) is ...... ed to a wide range of cancers.
@en
Link from a Wikipage to an external page
Wikipage page ID
10,474,358
page length (characters) of wiki page
Wikipage revision ID
1,021,595,156
Link from a Wikipage to another Wikipage
wikiPageUsesTemplate
hypernym
comment
CHEK2 (Checkpoint kinase 2) is ...... ed to a wide range of cancers.
@en
label
CHEK2
@en