Cadherin cytoplasmic region
In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins. A key determinant to the strength of the binding that it is mediated by cadherins is the juxtamembrane region (the part of the cytoplasmic region which is adjacent to the transmembrane domain) of the cadherin. This region induces clustering and also binds to the protein catenin (p120ctn). The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly through interaction with the cytoskeleton.
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Cadherin cytoplasmic region
In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins. A key determinant to the strength of the binding that it is mediated by cadherins is the juxtamembrane region (the part of the cytoplasmic region which is adjacent to the transmembrane domain) of the cadherin. This region induces clustering and also binds to the protein catenin (p120ctn). The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly through interaction with the cytoskeleton.
has abstract
In molecular biology, the cadh ...... raction with the cytoskeleton.
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Symbol
Cadherin_C
Wikipage page ID
32,179,247
page length (characters) of wiki page
Wikipage revision ID
994,845,225
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caption
beta-catenin/e-cadherin complex
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InterPro
IPR000233
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name
Cadherin_C
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Pfam
PF01049
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symbol
Cadherin_C
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wikiPageUsesTemplate
subject
hypernym
comment
In molecular biology, the cadh ...... raction with the cytoskeleton.
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label
Cadherin cytoplasmic region
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