Calitoxin
Calitoxin, also known as CLX, is a sea anemone neurotoxin produced by the sea anemone Calliactis parasitica. It targets crabs and octopuses, among other invertebrates. Two isoforms (CLX-1 and CLX-2) have been identified, both of which are formed from precursors stored in the stinging cells of the anemone. Once the toxin is activated and released, it causes paralysis by increasing neurotransmitter release at invertebrate neuromuscular junctions. Along with several other toxins derived from anemones, CLX is useful in ion channel research. Certain structural aspects of calitoxin are dissimilar from sea anemone toxins that also target the sodium ion channels. Other toxins resembling calitoxin function in completely different ways.
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Calitoxin
Calitoxin, also known as CLX, is a sea anemone neurotoxin produced by the sea anemone Calliactis parasitica. It targets crabs and octopuses, among other invertebrates. Two isoforms (CLX-1 and CLX-2) have been identified, both of which are formed from precursors stored in the stinging cells of the anemone. Once the toxin is activated and released, it causes paralysis by increasing neurotransmitter release at invertebrate neuromuscular junctions. Along with several other toxins derived from anemones, CLX is useful in ion channel research. Certain structural aspects of calitoxin are dissimilar from sea anemone toxins that also target the sodium ion channels. Other toxins resembling calitoxin function in completely different ways.
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Calitoxin, also known as CLX, ...... in completely different ways.
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Wikipage page ID
44,092,786
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Wikipage revision ID
987,186,543
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InterPro
IPR000693
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name
Calitoxin-1
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Calitoxin-2
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Organism
Pfam
PF00706
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symbol
CLX-1
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CLX-2
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Toxin_4
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UniProt
P14531
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P49127
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wikiPageUsesTemplate
hypernym
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Calitoxin, also known as CLX, ...... in completely different ways.
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label
Calitoxin
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