Canakinumab
Canakinumab (INN), sold under the brand name Ilaris is a medication for the treatment of systemic juvenile idiopathic arthritis (SJIA) and active Still's disease, including adult-onset Still's disease (AOSD). It is a human monoclonal antibody targeted at interleukin-1 beta. It has no cross-reactivity with other members of the interleukin-1 family, including interleukin-1 alpha. Common side effects include infections (colds and upper respiratory tract infections), abdominal pain and injection-site reactions.
treatment
ACZ885ATC code L04ATC code L04AC08ATCvet code QL04AC08C6452H9958N1722O2010S42Cold urticariaCryopyrin-associated periodic syndromeEldad Ben-ChetritFamilial Mediterranean feverGoutIlarisInterleukin 1 betaList of drugs: C–CaList of drugs: Ia–IlList of drugs granted breakthrough therapy designationList of therapeutic monoclonal antibodiesMevalonate kinase deficiencyMonoclonal antibody therapyMuckle–Wells syndromeNeonatal-onset multisystem inflammatory diseaseNovartisPaul RidkerPericarditisPeriodic fever syndromePyoderma gangrenosumSystemic-onset juvenile idiopathic arthritisYao syndrome
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treatment
primaryTopic
Canakinumab
Canakinumab (INN), sold under the brand name Ilaris is a medication for the treatment of systemic juvenile idiopathic arthritis (SJIA) and active Still's disease, including adult-onset Still's disease (AOSD). It is a human monoclonal antibody targeted at interleukin-1 beta. It has no cross-reactivity with other members of the interleukin-1 family, including interleukin-1 alpha. Common side effects include infections (colds and upper respiratory tract infections), abdominal pain and injection-site reactions.
has abstract
Canakinumab (Handelsname Ilari ...... von Blut-Monozyten produziert.
@de
Canakinumab (INN), sold under ...... and injection-site reactions.
@en
Canaquinumabe (nome comercial ...... ibidor de interleucina-1 beta.
@pt
Il Canakinumab (nome commercia ...... ischio di morte per infezione.
@it
Kanakinumab (nazwa handlowa Il ...... 1, włącznie z interleukiną 1α.
@pl
Le canakinumab est un anticorps monoclonal dirigé contre l'interleukine 1 bêta.
@fr
Канакинумаб (МНН), продаваемый ...... те и реакции в месте инъекции.
@ru
Канакінумаб (англ. Canakinumab ...... а також зниження частоти раку.
@uk
كاناكينوماب هو جسم مضاد وحيد ا ...... اج مرض الانسداد الرئوي المزمن.
@ar
カナキヌマブ（Canakinumab）は、インターロイキン- ...... 自己免疫疾患の一種で、家族性寒冷アレルギー、、等が含まれる。
@ja
alternative name
Ilaris
@en
CAS number
914613-48-2
ChEMBL
DrugBank
FDA UNII code
37CQ2C7X93
KEGG
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Wikipage page ID
12,148,828
page length (characters) of wiki page
Wikipage revision ID
984,344,642
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ATC prefix
L04
@en
ATC suffix
AC08
@en
caption
Ribbon diagram of canakinumab bound to IL-1β from PDB entry
@en
CAS number
ChEMBL
ChemSpiderID
none
@en
DailyMedID
Canakinumab
@en
DrugBank
DB06168
@en
KEGG
D09315
@en
legal status
Rx-only
@en
legal US
Rx-only
@en
licence EU
yes
@en
licence US
Canakinumab
@en
mab type
mab
@en
molecular weight
pregnancy AU
B3
@en
pregnancy US
N
@en
routes of administration
source
u
@en
synonyms
ACZ885, ACZ-885
@en
target
tradename
Ilaris
@en
type
mab
@en
Verifiedfields
changed
@en
verifiedrevid
460,015,774
Watchedfields
changed
@en
wikiPageUsesTemplate
hypernym
comment
Canakinumab (Handelsname Ilari ...... von Blut-Monozyten produziert.
@de
Canakinumab (INN), sold under ...... and injection-site reactions.
@en
Canaquinumabe (nome comercial ...... ibidor de interleucina-1 beta.
@pt
Il Canakinumab (nome commercia ...... nzialmente letali. Inoltre, Il
@it
Kanakinumab (nazwa handlowa Il ...... 1, włącznie z interleukiną 1α.
@pl
Le canakinumab est un anticorps monoclonal dirigé contre l'interleukine 1 bêta.
@fr
Канакинумаб (МНН), продаваемый ...... те и реакции в месте инъекции.
@ru
Канакінумаб (англ. Canakinumab ...... а також зниження частоти раку.
@uk
كاناكينوماب هو جسم مضاد وحيد ا ...... اج مرض الانسداد الرئوي المزمن.
@ar
カナキヌマブ（Canakinumab）は、インターロイキン- ...... 自己免疫疾患の一種で、家族性寒冷アレルギー、、等が含まれる。
@ja
label
Canakinumab
@de
Canakinumab
@en
Canakinumab
@fr
Canakinumab
@it
Canaquinumabe
@pt
Kanakinumab
@pl
Канакинумаб
@ru
Канакінумаб
@uk
كاناكينوماب
@ar
カナキヌマブ
@ja