Charlotte Serber (née Leof; July 26, 1911 – May 22, 1967) was an American journalist, statistician and librarian. She was the librarian of the Manhattan Project's Los Alamos Laboratory during World War II, and the laboratory's only female group leader. After the war she attempted to secure a position as a librarian at the Radiation Laboratory in Berkeley, but was rejected for lack of a security clearance; the likely reason was due to her political views. She later became a production assistant for the Broadway Theatre, and an interviewer for Louis Harris.