Clorgiline
Clorgiline (INN), or clorgyline (BAN), is a monoamine oxidase inhibitor (MAOI) structurally related to pargyline which is described as an antidepressant. Specifically, it is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). Clorgiline was never marketed, but it has found use in scientific research. It has been found to bind with high affinity to the σ1 receptor (Ki = 3.2 nM) and with very high affinity to the I2 imidazoline receptor (Ki = 40 pM).
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Clorgiline
Clorgiline (INN), or clorgyline (BAN), is a monoamine oxidase inhibitor (MAOI) structurally related to pargyline which is described as an antidepressant. Specifically, it is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). Clorgiline was never marketed, but it has found use in scientific research. It has been found to bind with high affinity to the σ1 receptor (Ki = 3.2 nM) and with very high affinity to the I2 imidazoline receptor (Ki = 40 pM).
has abstract
A harmina é um alcalóide harma ...... AO-B), contudo, não é inibido.
@pt
Clorgilina es un inhibidor irr ...... relacionada con la pargilina.
@es
Clorgiline (INN), or clorgylin ...... azoline receptor (Ki = 40 pM).
@en
Harmin (summaformel C13H12N2O) ...... till genom att lägga till den.
@sv
Harmina – organiczny związek c ...... MAO-A oraz słabym stymulantem.
@pl
L'harmine, aussi appelée télép ...... spèce qu'il fut isolé en 1841.
@fr
La armina è un alcaloide fluor ...... enzima che scompone monoamine.
@it
La harmina es un alcaloide flu ...... no inhibe la variante MAO-B.
@es
Гарми́н — бета-карболиновый ал ...... иридо[3,4-b]индол (гармин)..."
@ru
クロルギリン(Clorgiline)は、不可逆でA選択的なモノアミン酸化酵素阻害薬で、科学研究用途に用いられる。構造的にパルギリンと関連する。
@ja
CAS number
17780-72-2
ChEMBL
DrugBank
FDA UNII code
LYJ16FZU9Q
KEGG
PubChem
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
1,017,006,702
Link from a Wikipage to another Wikipage
ATC prefix
none
@en
CAS number
ChEBI
ChEMBL
ChemSpiderID
DrugBank
DB04017
@en
IUPAC name
N-[3-propyl]-N-methyl-prop-2-yn-1-amine
@en
IUPHAR ligand
KEGG
D03248
@en
legal status
Uncontrolled
@en
PubChem
SMILES
Clc1ccccc1OCCCNC
@en
StdInChIKey
BTFHLQRNAMSNLC-UHFFFAOYSA-N
@en
UNII
LYJ16FZU9Q
@en
Verifiedfields
changed
@en
verifiedrevid
443,677,087
wikiPageUsesTemplate
subject
hypernym
comment
A harmina é um alcalóide harma ...... AO-B), contudo, não é inibido.
@pt
Clorgilina es un inhibidor irr ...... relacionada con la pargilina.
@es
Clorgiline (INN), or clorgylin ...... azoline receptor (Ki = 40 pM).
@en
Harmin (summaformel C13H12N2O) ...... till genom att lägga till den.
@sv
Harmina – organiczny związek c ...... MAO-A oraz słabym stymulantem.
@pl
L'harmine, aussi appelée télép ...... spèce qu'il fut isolé en 1841.
@fr
La armina è un alcaloide fluor ...... enzima che scompone monoamine.
@it
La harmina es un alcaloide flu ...... no inhibe la variante MAO-B.
@es
Гарми́н — бета-карболиновый ал ...... иридо[3,4-b]индол (гармин)..."
@ru
クロルギリン(Clorgiline)は、不可逆でA選択的なモノアミン酸化酵素阻害薬で、科学研究用途に用いられる。構造的にパルギリンと関連する。
@ja
label
Armina
@it
Clorgilina
@es
Clorgiline
@en
Harmin
@de
Harmin
@sv
Harmina
@es
Harmina
@pl
Harmina
@pt
Harmine
@fr
Гармин
@ru