Clydesdale South is one of the twenty wards used to elect members of the South Lanarkshire Council. It elects three councillors. Its territory covers a primarily rural area in western Clydesdale bisected by the M74 motorway; the largest settlements are Blackwood/Kirkmuirhill and Lesmahagow, also including villages such as Coalburn, Douglas and Rigside – these boundaries were unaffected by a 2017 national review. In 2019, the ward had a population of 14,647.