Cutshamekin (died in 1654) (also spelled Kitchamakin, Kuchamakin, or Cutshumaquin) was a Native American leader, who was a sachem of the Massachusett tribe based along the Neponset River and Great Blue Hill in what is now Dorchester, Massachusetts and Milton, Massachusetts before becoming one of the first leaders of the praying Indian town of Natick, Massachusetts. He is the possible namesake of Jamaica Plain.