DiFMDA
Difluoromethylenedioxyamphetamine (DiFMDA) is a substituted derivative of 3,4-methylenedioxyamphetamine (MDA), which was developed by Daniel Trachsel and coworkers, along with the corresponding fluorinated derivatives of MDMA, MDEA, BDB and MBDB, with the aim of finding a non-neurotoxic drug able to be used as a less harmful substitute for entactogenic drugs such as MDMA. Since a major route of the normal metabolism of these compounds is scission of the methylenedioxy ring, producing neurotoxic metabolites such as alpha-methyldopamine, it was hoped that the difluoromethylenedioxy bioisostere would show increased metabolic stability and less toxicity.
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DiFMDA
Difluoromethylenedioxyamphetamine (DiFMDA) is a substituted derivative of 3,4-methylenedioxyamphetamine (MDA), which was developed by Daniel Trachsel and coworkers, along with the corresponding fluorinated derivatives of MDMA, MDEA, BDB and MBDB, with the aim of finding a non-neurotoxic drug able to be used as a less harmful substitute for entactogenic drugs such as MDMA. Since a major route of the normal metabolism of these compounds is scission of the methylenedioxy ring, producing neurotoxic metabolites such as alpha-methyldopamine, it was hoped that the difluoromethylenedioxy bioisostere would show increased metabolic stability and less toxicity.
has abstract
Difluoromethylenedioxyamphetam ...... ed drugs would be in practice.
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CAS number
910393-51-0
FDA UNII code
8Q2ANL037S
PubChem
Wikipage page ID
31,366,022
page length (characters) of wiki page
Wikipage revision ID
992,450,153
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ATC prefix
none
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CAS number
ChemSpiderID
26,495,356
IUPAC name
legal CA
Schedule I
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legal DE
NpSG
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legal UK
Class A
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PubChem
57,467,735
SMILES
CCN
@en
StdInChIKey
BHDXKBALNFHXDV-UHFFFAOYSA-N
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Verifiedfields
changed
@en
verifiedrevid
451,607,745
wikiPageUsesTemplate
subject
hypernym
comment
Difluoromethylenedioxyamphetam ...... c stability and less toxicity.
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label
DiFMDA
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