Dr. Thomas E. Lucas House is a historic home located at Chesterfield, Chesterfield County, South Carolina. It was built about 1868, and is a two-story, three bay, central-hall plan, frame farmhouse, with a one-story rear wing. It features a one-story porch across the front façade. Also on the property is an antebellum smokehouse, a gazebo (originally used as a hothouse, c. 1885), and several other outbuildings. The house is associated with Dr. Thomas E. Lucas, a farmer, physician and politician. In 1864 Lucas resigned his position as a lieutenant in Company A in the Fifteenth Battalion, South Carolina Artillery, to serve in the South Carolina House of Representatives.