Clayton Earl Desmond (9 March 1894 – 14 July 1968) was a National Government and Progressive Conservative party member of the House of Commons of Canada. He was born in Morpeth, Ontario and became a farmer by career. He was first elected to Parliament at the Kent riding in the 1940 general election under the National Government affiliation, then re-elected as a Progressive Conservative for a second term in 1945. He was defeated by Blake Huffman of the Liberal party in the 1949 election.