Edward Johnson (1767–1829) was an American politician and businessman. He was a native of Baltimore, Maryland and served as that city's mayor for six terms between 1808 and 1824. A staunch member of Jefferson's Democratic-Republican Party, he led Baltimore during the War of 1812 and was instrumental in organizing the civilian defense of the city. For several years he was the owner of one of Baltimore's largest breweries and also served as a director of the Bank of Baltimore.