Esperance Plains, also known as Eyre Botanical District, is a biogeographic region in southern Western Australia on the south coast between the Avon Wheatbelt and Hampton regions, and bordered to the north by the Mallee region. It is a plain punctuated by granite and quartz outcrops and ranges, with a semi-arid Mediterranean climate and vegetation consisting mostly of mallee-heath and proteaceous scrub. About half of the region has been cleared for intensive agriculture. Recognised as a bioregion under the Interim Biogeographic Regionalisation for Australia (IBRA), it was first defined by John Stanley Beard in 1980.