Euphorbia garberi (syn. Chamaesyce garberi) is a rare species of flowering plant in the euphorb family known by the common name Garber's spurge. It is endemic to Florida, where there are 17 known occurrences, fourteen of which are located on fourteen separate islands of the Florida Keys. The populations vary in size, with four containing fewer than 20 plants each and one containing over one million. The plant has been reduced to a small portion of its former distribution and remaining populations are threatened by a number of processes. This is a federally listed threatened species of the United States.