Eva K Lee is an American applied mathematician and operations researcher who applies combinatorial optimization and systems biology to the study of health care decision making and organizational transformation. She is a professor at the H. Milton Stewart School of Industrial and Systems Engineering of Georgia Institute of Technology. She is also the Founder and Director of the Center for Operations Research in Medicine and Healthcare since 1999. She is a Distinguished Scholar in Health Systems, Health System Institute at Georgia Tech and Emory University. Lee was named the Virginia C. and Joseph C. Mello Chair from 2017 to 2019.