The F. Julius LeMoyne House is a historic house museum at 49 East Maiden Street in Washington, Pennsylvania. Built in 1812, it was the home of Dr. Francis Julius LeMoyne (1798–1897), an antislavery activist who used it as a stop on the Underground Railroad. LeMoyne also assisted in the education of freed slaves after the American Civil War, founding the historically black LeMoyne–Owen College in Memphis, Tennessee. His house, now operated as a museum by the local historical society, was designated a National Historic Landmark in 1997. It is designated as a historic public landmark by the Washington County History & Landmarks Foundation.