Francisca Aparicio, 1st Marquis of Vistabella (23 July 1858 – 31 January 1943) was the First Lady of Guatemala between 1874 and 1885, performing the state duties required for the post. After her husband's death, she moved with her seven children to New York City and was well known for her entertainments. In 1892, she married a Spanish parliamentarian and moved to Europe, where her children were educated. Two paintings of her, painted by Francisco Masriera y Manovens are in the collection of the Museo del Prado in Madrid. When she was 14, she married Justo Rufino Barrios and immediately became the first Guatemalan First Lady in history to take office.