GATA2
GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively. The gene and its product are targets for the treatment of these diseases.
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Acute myeloid leukemiaAorta-gonad-mesonephrosCD27COUP-TFIIChronic myelomonocytic leukemiaEGFL7Emberger syndromeEpstein–Barr virus-associated lymphoproliferative diseasesErythropoietinGATA1GATA2 (gene)GATA2 deficiencyGATA transcription factorHDAC3Histone acetyltransferaseIKZF1LMO2List of human protein-coding genes 2LymphedemaMonoMACMonoamine oxidase AMyelodysplastic syndromeNeuronal lineage markerPioneer factorPituitary-specific positive transcription factor 1Promyelocytic leukemia proteinPulmonary alveolar proteinosisRUNX1SPI1Sensorineural hearing lossSevere congenital neutropeniaSmall MafZFPM2ZNF337Zinc finger and BTB domain-containing protein 16
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GATA2
GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively. The gene and its product are targets for the treatment of these diseases.
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GATA2 or GATA-binding factor 2 ...... rogression of prostate cancer.
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GATA2 or GATA-binding factor 2 ...... e treatment of these diseases.
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GATA2
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