Gadsden's Wharf is a wharf located in Charleston, South Carolina. It was the first destination for an estimated 100,000 enslaved Africans during the peak of the international slave trade. Some researchers have estimated that 40% of the enslaved Africans in the United States landed at Gadsden's Wharf. At one point, the wharf was the largest in America. The wharf is now home to the South Carolina Aquarium and the International African American Museum which will open in 2022.