Gianfranco Masini (26 November 1937 – 18 June 1993) was an Italian orchestra conductor, primarily known for conducting opera. During the course of his career he was a principal conductor at the Teatro Lirico Giuseppe Verdi in Trieste and at the Arena di Verona Festival. He appeared in numerous opera houses in Europe and North America as a guest conductor and was the principal guest conductor of the Stadttheater Bonn in 1990. At the time of his death, he was the principal conductor and artistic director of Montpellier Opera.