Guzamn is one of the woredas in the Amhara Region of Ethiopia. Part of the East Gojjam Zone, Guzamn is bordered on the southeast by Baso Liben, on the south by the Abay River which separates it from the Oromia Region, on the west by Debre Elias, on the northwest by Machakel, on the north by Sinan, and on the east by Aneded; the Chamwaga River defines part of the border between the Guzamn and Baso Liben woredas. The town and woreda of Debre Marqos is an enclave inside Guzamn. Towns in Guzamn include and . Sinan woreda was separate from Guzamn.