The Grand Hotel Quisisana is the largest and one of the best known hotels on the island of Capri. It is located in the heart of the old town of Capri, opposite the Hotel Residenza Capri and the Villa Sanfelice, to the south of the Piazza Umberto I. Set in gardens with "sprawling buildings [which] are painted a distinctive yellow and accented with vines," it is also a notable dining venue in the historic centre of Capri. British doctor George Sidney Clark established a sanatorium in 1845, turning it into the Grand Hotel Quisisana in 1861. "Qui si sana" means "here one heals" in Italian.