HLA-A
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I transmembrane proteins. The others are HLA-B and HLA-C. The protein is a heterodimer, and is composed of a heavy α chain and smaller β chain. The α chain is encoded by a variant , and the β chain (β2-microglobulin) is an invariant β2 microglobulin molecule. The β2 microglobulin protein is encoded by the B2M gene, which is located at chromosome 15q21.1 in humans.
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A30-Cw5-B18-DR3-DQ2_(HLA_Haplotype)Acute generalized exanthematous pustulosisAlan M. KrenskyCD8AChromosome 6Diffuse panbronchiolitisDrug reaction with eosinophilia and systemic symptomsEslicarbazepine_acetateGenetic studies on SinhaleseGraft-versus-host diseaseHLA-A*02HLA-A1HLA-A10HLA-A11HLA-A19HLA-A23HLA-A24HLA-A28HLA-A3HLA-A9HLA-A (gene)HLA-BHLA-B*83HLA-B13HLA-B14HLA-B18HLA-B35HLA-B37HLA-B38HLA-B39HLA-B41HLA-B42HLA-B44HLA-B45HLA-B46HLA-B47HLA-B48HLA-B49HLA-B50HLA-B51
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HLA-A
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I transmembrane proteins. The others are HLA-B and HLA-C. The protein is a heterodimer, and is composed of a heavy α chain and smaller β chain. The α chain is encoded by a variant , and the β chain (β2-microglobulin) is an invariant β2 microglobulin molecule. The β2 microglobulin protein is encoded by the B2M gene, which is located at chromosome 15q21.1 in humans.
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HLA-A is a group of human leuk ...... n on HIV/AIDS progression is .
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1,025,219,819
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function
Peptide presentation for immune recognition
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gene
HLA-A
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heteropolymer
MHC class I, A
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image source
Illustration of HLA-A
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locus
Chromosome 15q22
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Chromosome 6p21.3
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polymer type
heterodimer
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protein type
subunit
α
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β2M
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SubunitCount
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hypernym
comment
HLA-A is a group of human leuk ...... chromosome 15q21.1 in humans.
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label
HLA-A
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