HU-331
HU-331 is a quinone anticarcinogenic drug synthesized from cannabidiol, a cannabinoid in the Cannabis sativa plant. It showed a great efficacy against oncogenic human cells. HU-331 does not cause arrest in cell cycle, cell apoptosis or caspase activation. HU-331 inhibits DNA topoisomerase II even at nanomolar concentrations, but has shown a negligible effect on the action of DNA topoisomerase I. The cannabinoid quinone HU-331 is a very specific inhibitor of topoisomerase II, compared with most known anticancer quinones. One of the main objectives of these studies is the development of a new quinone derived compound that produces anti-neoplastic activity while maintaining low toxicity at therapeutic doses.
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HU-331
HU-331 is a quinone anticarcinogenic drug synthesized from cannabidiol, a cannabinoid in the Cannabis sativa plant. It showed a great efficacy against oncogenic human cells. HU-331 does not cause arrest in cell cycle, cell apoptosis or caspase activation. HU-331 inhibits DNA topoisomerase II even at nanomolar concentrations, but has shown a negligible effect on the action of DNA topoisomerase I. The cannabinoid quinone HU-331 is a very specific inhibitor of topoisomerase II, compared with most known anticancer quinones. One of the main objectives of these studies is the development of a new quinone derived compound that produces anti-neoplastic activity while maintaining low toxicity at therapeutic doses.
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HU-331 (3R,4R-pbenzoquinona-3- ...... principals en aquests estudis.
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HU-331 is a quinone anticarcin ...... toxicity at therapeutic doses.
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IUPAC name
3-Hydroxy-2-[(1R,6R)-3-methyl- ...... lcyclohexa-2,5-diene-1,4-dione
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30,693,119
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1,026,398,065
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HU-331 (3R,4R-pbenzoquinona-3- ...... principals en aquests estudis.
@ca
HU-331 is a quinone anticarcin ...... toxicity at therapeutic doses.
@en
label
HU-331
@ca
HU-331
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