Hada Labo (肌ラボ, Hada Rabo, "Skin Lab") is a Japanese skin care brand developed by Rohto Pharmaceutical. The brand is most known for their hyaluronic acid products, and for offering eco-friendly refill pouches. Their flagship offering, the Super Hyaluronic Acid Moisturizing Lotion, was the number one lotion in Japan for seven consecutive years. Distinct from Hado Labo proper, Hada Labo Tokyo is manufactured by Mentholatum (a subsidiary of Rohto) for the American market, differing in branding, products and formulation.