The Harriet Taylor Upton House is a historic house museum at 380 Mahoning Avenue NW in Warren, Ohio. Built about 1840, it was the residence of suffragette Harriet Taylor Upton (1853–1945) from 1887 to 1931. The house was the headquarters of Upton's National American Woman's Suffrage Association from 1903 to 1905, and was thus an important site in the early 20th century push for women's suffrage. It was designated a National Historic Landmark in 1992. It is owned by a local nonprofit, and is open for tours by appointment.