Holy Ghost College was one of the colleges of Leuven University, now listed as built heritage of Flanders, Belgium. The college was founded in 1442 when Louis de Rycke gave the University a former brewery that he owned to house seven poor students of the Faculty of Theology. The gift was confirmed on 5 June 1445, and was extended in 1462 when de Rycke bequeathed his own house and garden to the college. Other donations followed until the college owned the whole block in which it was situated. Renovations began in the 16th century and continued throughout the college's history. The current appearance derives from 18th-century renovations.