Hyper IgM syndrome
Hyper IgM syndrome describes a group of primary immune deficiency disorders characterized by defective CD40 signaling; via B cells affecting class switch recombination (CSR) and somatic hypermutation. Immunoglobulin (Ig) class switch recombination deficiencies are characterized by elevated serum Immunoglobulin M (IgM) levels and a considerable deficiency in Immunoglobulins G (IgG), A (IgA) and E (IgE). As a consequence, people with HIGM have decreased concentrations of serum IgG and IgA and normal or elevated IgM, leading to increased susceptibility to infections.
Asghar AghamohammadiCD154DysgammaglobulinemiaGamma globulinHans D. OchsHumoral immune deficiencyHyper-IgM syndromeHyper-IgM syndrome type 1Hyper-IgM syndrome type 2Hyper-IgM syndrome type 3Hyper-IgM syndrome type 4Hyper-IgM syndrome type 5Hyper-IgM syndromesHyper igm syndromeHypergammaglobulinemiaHypogammaglobulinemiaImmune disorderImmunodeficiency with increased IgMImmunodeficiency with increased immunoglobulin MList of ICD-9 codes 240–279: endocrine, nutritional and metabolic diseases, and immunity disordersList of diseases (H)List of hematologic conditionsList of immunologistsList of primary immunodeficienciesList of syndromesPneumocystis pneumoniaSevere congenital neutropeniaT helper cellWiskott–Aldrich syndrome
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Hyper IgM syndrome
Hyper IgM syndrome describes a group of primary immune deficiency disorders characterized by defective CD40 signaling; via B cells affecting class switch recombination (CSR) and somatic hypermutation. Immunoglobulin (Ig) class switch recombination deficiencies are characterized by elevated serum Immunoglobulin M (IgM) levels and a considerable deficiency in Immunoglobulins G (IgG), A (IgA) and E (IgE). As a consequence, people with HIGM have decreased concentrations of serum IgG and IgA and normal or elevated IgM, leading to increased susceptibility to infections.
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El síndrome de hiper-IgM es un ...... a inmunoglobulinas IgG e IgA.
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Hyper IgM syndrome describes a ...... susceptibility to infections.
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Mit Hyper-IgM-Syndrom, auch Ig ...... lin A im Blutserum bezeichnet.
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Per sindrome da iper-IgM, si i ...... posta da due forme specifiche.
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Zespoły hiper IgM – grupa pier ...... do zachorowania na chłoniaki.
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高免疫球蛋白M症候群是一種遺傳病，其會導致免疫球蛋白同型轉化 ...... 為X染色體隱性遺傳或體染色體隱性遺傳，視基因突變的位置而定。
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eMedicine subject
ped
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eMedicine topic
2457
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ICD10
ICD9
medical diagnosis
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1,022,003,764
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diagnosis
MRI, Chest radiography
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eMedicineSubj
ped
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eMedicineTopic
ICD
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D053306
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name
Hyper IgM syndrome
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symptoms
Chronic diarrhea
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treatment
Allogeneic hematopoietic cell transplantation
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types
Hyper-IgM syndrome type 1,2,3,4 and 5
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El síndrome de hiper-IgM es un ...... stinales por cryptosporidium.
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Hyper IgM syndrome describes a ...... susceptibility to infections.
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Mit Hyper-IgM-Syndrom, auch Ig ...... lin A im Blutserum bezeichnet.
@de
Per sindrome da iper-IgM, si i ...... posta da due forme specifiche.
@it
Zespoły hiper IgM – grupa pier ...... do zachorowania na chłoniaki.
@pl
高免疫球蛋白M症候群是一種遺傳病，其會導致免疫球蛋白同型轉化 ...... 為X染色體隱性遺傳或體染色體隱性遺傳，視基因突變的位置而定。
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label
Hyper IgM syndrome
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Hyper-IgM-Syndrom
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Sindrome da iper-IgM
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Síndrome de hiper-IgM
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Zespoły hiper IgM
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高免疫球蛋白M症候群
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name
Hyper IgM syndrome
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