Hypothalamic–pituitary–somatotropic axis
The hypothalamic–pituitary–somatotropic axis (HPS axis), or hypothalamic–pituitary–somatic axis, also known as the hypothalamic–pituitary–growth axis, is a hypothalamic–pituitary axis which includes the secretion of growth hormone (GH; somatotropin) from the somatotropes of the pituitary gland into the circulation and the subsequent stimulation of insulin-like growth factor 1 (IGF-1; somatomedin-1) production by GH in tissues such as, namely, the liver. Other hypothalamic–pituitary hormones such as growth hormone-releasing hormone (GHRH; somatocrinin), growth hormone-inhibiting hormone (GHIH; somatostatin), and ghrelin (GHS) are involved in the control of GH secretion from the pituitary gland. The HPS axis is involved in postnatal human growth. Individuals with growth hormone deficiency or
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AcromegalyAnterior pituitaryEC508GhrelinGigantismGrowth hormone deficiencyGrowth hormone receptorGrowth hormone secretagogueGrowth hormone–releasing hormoneHPS axisHypopituitarismHypothalamic-pituitary-growthHypothalamic-pituitary-growth axisHypothalamic-pituitary-somaticHypothalamic-pituitary-somatic axisHypothalamic-pituitary-somatotropicHypothalamic-pituitary-somatotropic axisHypothalamic–pituitary hormoneHypothalamic–pituitary–growthHypothalamic–pituitary–growth axisHypothalamic–pituitary–somaticHypothalamic–pituitary–somatic axisHypothalamic–pituitary–somatotropicInsulin-like growth factor 1 receptorLaron syndromeOpioid-induced endocrinopathySomatopauseSomatostatinSomatotropic cell
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Hypothalamic–pituitary–somatotropic axis
The hypothalamic–pituitary–somatotropic axis (HPS axis), or hypothalamic–pituitary–somatic axis, also known as the hypothalamic–pituitary–growth axis, is a hypothalamic–pituitary axis which includes the secretion of growth hormone (GH; somatotropin) from the somatotropes of the pituitary gland into the circulation and the subsequent stimulation of insulin-like growth factor 1 (IGF-1; somatomedin-1) production by GH in tissues such as, namely, the liver. Other hypothalamic–pituitary hormones such as growth hormone-releasing hormone (GHRH; somatocrinin), growth hormone-inhibiting hormone (GHIH; somatostatin), and ghrelin (GHS) are involved in the control of GH secretion from the pituitary gland. The HPS axis is involved in postnatal human growth. Individuals with growth hormone deficiency or
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The hypothalamic–pituitary–som ...... h growth hormone deficiency or
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Hypothalamic–pituitary–somatotropic axis
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