Isabelle Graesslé (born 23 February 1959) is a French born theologian, feminist and former museum director, based in Geneva. In 2001 she was appointed moderator of ministers and deacons at the Protestant Church of Geneva. The position dates back to 1541 when it was created by John Calvin, but Graesslé, after 460 years, was the first woman to occupy it. In 2004 she was appointed the first director of the International Reformation Museum which opened the next year in Geneva, but she resigned the post in 2016. It was indicated that her departure followed disagreement about levels of funding.