James Rosco (died 1761) was a British stage actor. His name is also written as James Roscoe. From 1722 to 1729 he acted at the Smock Alley Theatre in Dublin. Moving to London he appeared at a variety of venues, including the Drury Lane and Haymarket Theatres before spending several years as a member of Henry Giffard's company at the Goodman's Fields Theatre near the Tower of London. After Giffard's attempt to challenge the patent theatres was ended by the Licensing Act he joined Covent Garden where he performed regularly between 1737 and 1748. He was generally a secondary performer at the company, scarcely playing leading roles. In 1739 he was accidentally stabbed during a performance of Mariamne.