Johannes Leimena (6 March 1905 – 29 March 1977) was a Moluccan politician and physician who is a National Hero of Indonesia. He was one of the longest-serving government ministers in Indonesia and the longest-serving under Sukarno's presidency, most prominently filling the roles of Deputy Prime Minister and Minister of Health. He also served in the People's Representative Council and the Constitutional Assembly. An Ambonese Christian, he was a member of the Indonesian Christian Party (Parkindo) and was its chairman between 1950 and 1961.