Karen Murphy, R.N., Ph.D., (born ?) is an American registered nurse and healthcare administrator. She previously served as the Pennsylvania Secretary of Health, having been nominated by Pennsylvania Governor Tom Wolf and confirmed in May 2015. Prior to that, she served as Pennsylvania Director of the State Innovation Models Initiative and CEO of the Moses Taylor Health System. Murphy received a registered nurse diploma from the Scranton State Hospital School of Nursing. She holds a Bachelor of Science from the University of Scranton (1991), a Master of Business Administration from Marywood University, and a Doctorate of Philosophy in Business Administration from the Fox School of Business and Management at Temple University. Murphy worked at Moses Taylor Hospital in Scranton, Pennsylvania,