Karl von Mansfeld (1543 – 24 August 1595) was a German general during the Cologne War and the Ottoman-Habsburg wars. Von Mansfeld was the son of Count Peter Ernst I von Mansfeld-Vorderort, born in present-day Luxembourg, and was educated in France. He entered the military of Philip II of Spain, and was appointed a general and an admiral in the navy of the Spanish Netherlands. He was sent to Hungary, where along with Count Mátyás Cseszneky he participated in the siege of Esztergom in 1595 during the Long War. He died shortly thereafter, probably of his wounds, in Komárom.