L'assedio di Calais (The siege of Calais) is an 1836 melodramma lirico, or opera, in three acts by Gaetano Donizetti, his 49th opera. Salvatore Cammarano wrote the Italian libretto, which has been described as "...a remarkable libretto, the closest Cammarano ever got to real poetry, particularly in his description of the embattled city and the heartfelt pride of its citizens". It was based on Luigi Marchionni's play L'assedio di Calais (also called Edoardo III), which had been presented in Naples around 1825, and secondarily on Luigi Henry's ballet L'assedio di Calais, which had been performed in Naples in 1828 and revived in 1835.