List of St. Louis Cardinals first-round draft picks

The St. Louis Cardinals are a Major League Baseball (MLB) franchise based in St. Louis, Missouri. They play in the National League Central division. Since the institution of MLB's Rule 4 Draft, the Cardinals have selected 77 players in the first round. Officially known as the "First-Year Player Draft", the Rule 4 Draft is MLB's primary mechanism for assigning amateur baseball players from high schools, colleges, and other amateur baseball clubs to its teams. The draft order is determined based on the previous season's standings, with the team possessing the worst record receiving the first pick. In addition, teams which lost free agents in the previous off-season may be awarded compensatory or supplementary picks.

List of St. Louis Cardinals first-round draft picks

The St. Louis Cardinals are a Major League Baseball (MLB) franchise based in St. Louis, Missouri. They play in the National League Central division. Since the institution of MLB's Rule 4 Draft, the Cardinals have selected 77 players in the first round. Officially known as the "First-Year Player Draft", the Rule 4 Draft is MLB's primary mechanism for assigning amateur baseball players from high schools, colleges, and other amateur baseball clubs to its teams. The draft order is determined based on the previous season's standings, with the team possessing the worst record receiving the first pick. In addition, teams which lost free agents in the previous off-season may be awarded compensatory or supplementary picks.