List of phenyltropanes
Phenyltropanes (PTs) are a family of chemical compounds originally derived from structural modification of cocaine. The main feature differentiating phenyltropanes from cocaine is that they lack the ester functionality at the 3-position terminating in the benzene; and thusly the phenyl is attached direct to the tropane skeleton with no further (therefore the name "phenyl"-tropane) that the cocaine benzoyloxy provided. The original purpose of which was to extirpate the cardiotoxicity inherent in the local anesthetic "numbing" capability of cocaine (since the methylated benzoate ester is essential to cocaine's blockage of sodium channels which cause topical anesthesia) while retaining stimulant function. These compounds present many different avenues of research into therapeutic application
Wikipage redirect
(R)-p-Isothiocyanatobenzoylecgonine methyl esterBioorganometallic chemistryDichloropaneList of PTsList of PhenyltropanesList of benzimidazole opioidsList of cocaine analoguesList of fentanyl analoguesList of methylphenidate analoguesList of phenyltropanesNalorphineO-4210PhenyltropanePi-Stacking (chemistry)RTI-120RTI-121RTI-171RTI-229RTI-274RTI-331RTI-332RTI-333RTI-371RTI-42291,2-dimethoxyethaanRTI-56Substituted phenylmorpholineTroparil1,2-dimethoxyethaan
Link from a Wikipage to another Wikipage
primaryTopic
List of phenyltropanes
Phenyltropanes (PTs) are a family of chemical compounds originally derived from structural modification of cocaine. The main feature differentiating phenyltropanes from cocaine is that they lack the ester functionality at the 3-position terminating in the benzene; and thusly the phenyl is attached direct to the tropane skeleton with no further (therefore the name "phenyl"-tropane) that the cocaine benzoyloxy provided. The original purpose of which was to extirpate the cardiotoxicity inherent in the local anesthetic "numbing" capability of cocaine (since the methylated benzoate ester is essential to cocaine's blockage of sodium channels which cause topical anesthesia) while retaining stimulant function. These compounds present many different avenues of research into therapeutic application
has abstract
Phenyltropanes (PTs) are a fam ...... at have been made and studied.
@en
Link from a Wikipage to an external page
Wikipage page ID
24,325,591
page length (characters) of wiki page
Wikipage revision ID
1,024,560,213
Link from a Wikipage to another Wikipage
align
left
@en
caption
R-97a & S-97b , both examples ...... reation of like-series of PTs.
@en
RTI-4229-470 structure. Highly excited 94 pM DAT signal.
@en
para-chloro
@en
para-hydro
@en
↑ above: 2D skeletal depiction.
@en
↓ below: 3D tube model.
@en
date
May 2019
@en
direction
horizontal
@en
vertical
@en
header
Compound 48
@en
image
@en
@en
@en
@en
@en
@en
reason
unencyclopediac details in tables: compound-numbers specific to certain references
@en
wikiPageUsesTemplate
hypernym
comment
Phenyltropanes (PTs) are a fam ...... h into therapeutic application
@en
label
List of phenyltropanes
@en