Lobos (Spanish: Isla de Lobos, pronounced [ˈizla ðe ˈloβos]) is a big island in Uruguay, at the confluence of Negro River (Spanish: Río Negro) and Uruguay River. Politically it belongs to Rio Negro department. Up to the 19th century, the island was actually three islets, the largest called Vizcaíno, same as the island across the Yaguarí Creek.