Ludwig Johann Wilhelm Gruno von Hessen-Homburg (15 January 1705 – 23 October 1745) was hereditary prince of Hesse-Homburg and an Imperial Russian field marshal. He was the eldest surviving son of Frederick III, Landgrave of Hesse-Homburg and his wife Princess Elisabeth Dorothea of Hesse-Darmstadt, daughter of Louis VI, Landgrave of Hesse-Darmstadt. He studied at the University of Giessen and was sent by his father to Russia in 1723. He died from illness on a travel in Berlin. He pre-deceased his father and was buried in the crypt of Bad Homburg Castle.