The Luther Brannon House was a stone bungalow structure at 151 Oak Ridge Turnpike in Oak Ridge, Tennessee, United States, where it was one of the few buildings remaining from before World War II. The house was built in 1941 by Owen Hackworth and just months later was acquired by the U.S. Army for the Manhattan Project. It was one of about 180 existing structures that were spared from demolition after the area was acquired for Manhattan Project production activities. The house is believed to have been used as headquarters for local project operations and living quarters for General Leslie Groves until the Army completed construction of new administration buildings.