Lymphocyte function-associated antigen 1
Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which is the process by which leukocytes leave the bloodstream to enter the tissues. LFA-1 also mediates firm arrest of leukocytes. Additionally, LFA-1 is involved in the process of cytotoxic T cell mediated killing as well as antibody mediated killing by granulocytes and monocytes. As of 2007, LFA-1 has 6 known ligands: ICAM-1, ICAM-2, ICAM-3, ICAM-4, ICAM-5, and JAM-A. LFA-1/ICAM-1 interactions have recently been shown to stimulate signaling pathways that influence T cell differentiation. LFA-1 belongs to the integrin superfamily of adhesion molecules.
Alan M. KrenskyBronchus-associated lymphoid tissueCD11EfalizumabErlizumabFollicular dendritic cellsGut-specific homingHIVICAM-1ICAM3IcosImmune toleranceImmunological synapseImmunomodulatory imide drugIndex of immunology articlesIntegrinIntegrin alpha LIntegrin beta 2Intercellular adhesion moleculeJunctional adhesion moleculeLFA-1LFA1Leukocyte adhesion deficiencyLeukocyte adhesion deficiency-1Leukocyte extravasationLfa1LifitegrastList of MeSH codes (D12.776.395)List of MeSH codes (D12.776.543)List of MeSH codes (D23)List of human clusters of differentiationList of therapeutic monoclonal antibodiesLymphocyte function-associated antigenLymphocyte function-associated antigen-1Lymphocyte function antigen-1Lymphocyte functional antigen 1Lymphocyte homing receptorMRASMarginal zone B-cellMurine respirovirus
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Lymphocyte function-associated antigen 1
Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which is the process by which leukocytes leave the bloodstream to enter the tissues. LFA-1 also mediates firm arrest of leukocytes. Additionally, LFA-1 is involved in the process of cytotoxic T cell mediated killing as well as antibody mediated killing by granulocytes and monocytes. As of 2007, LFA-1 has 6 known ligands: ICAM-1, ICAM-2, ICAM-3, ICAM-4, ICAM-5, and JAM-A. LFA-1/ICAM-1 interactions have recently been shown to stimulate signaling pathways that influence T cell differentiation. LFA-1 belongs to the integrin superfamily of adhesion molecules.
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LFA-1 (интегрин αLβ2; англ. Ly ...... йкоцитов к участку воспаления.
@ru
La LFA-1 est une molécule d'ad ...... t à la surface des leucocytes.
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Lymphocyte function-associated ...... rfamily of adhesion molecules.
@en
淋巴球功能性抗原1(英文:Lymphocyte functi ...... 示LFA-1與ICAM-1的互動能刺激T細胞分化的傳訊途徑。
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LFA-1 (интегрин αLβ2; англ. Ly ...... йкоцитов к участку воспаления.
@ru
La LFA-1 est une molécule d'ad ...... t à la surface des leucocytes.
@fr
Lymphocyte function-associated ...... rfamily of adhesion molecules.
@en
淋巴球功能性抗原1(英文:Lymphocyte functi ...... 示LFA-1與ICAM-1的互動能刺激T細胞分化的傳訊途徑。
@zh
label
LFA-1
@fr
LFA-1
@ru
Lymphocyte function-associated antigen 1
@en
淋巴球功能性抗原1
@zh