Mendelian randomization
In epidemiology, Mendelian randomization is a method of using measured variation in genes of known function to examine the causal effect of a modifiable exposure on disease in observational studies. The design was first proposed in 1986 and subsequently described by Gray and Wheatley as a method for obtaining unbiased estimates of the effects of a putative causal variable without conducting a traditional randomised trial. These authors also coined the term Mendelian randomization. The design has a powerful control for reverse causation and confounding, which often impede or mislead epidemiological studies.
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Behavioural geneticsCausal modelDavid Evans (geneticist)Deborah LawlorExpected progeny differenceGenetic correlationGenetic epidemiologyGeneticsGenome-wide complex trait analysisGeorge Davey SmithIoanna TzoulakiJUPITER trialList of statistics articlesMRMendelian randomisationPolygenic scoreShantanu SenguptaTwin study
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Mendelian randomization
In epidemiology, Mendelian randomization is a method of using measured variation in genes of known function to examine the causal effect of a modifiable exposure on disease in observational studies. The design was first proposed in 1986 and subsequently described by Gray and Wheatley as a method for obtaining unbiased estimates of the effects of a putative causal variable without conducting a traditional randomised trial. These authors also coined the term Mendelian randomization. The design has a powerful control for reverse causation and confounding, which often impede or mislead epidemiological studies.
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Die Mendelsche Randomisierung ...... he Studie kontrolliert werden.
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Em epidemiologia, randomização ...... alham estudos epidemiológicos.
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En epidemiología, la aleatoriz ...... los estudios epidemiológicos.
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In epidemiology, Mendelian ran ...... slead epidemiological studies.
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Mendeliaanse randomisatie is e ...... epidemiologische onderzoeken.
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Die Mendelsche Randomisierung ...... he Studie kontrolliert werden.
@de
Em epidemiologia, randomização ...... alham estudos epidemiológicos.
@pt
En epidemiología, la aleatoriz ...... los estudios epidemiológicos.
@es
In epidemiology, Mendelian ran ...... slead epidemiological studies.
@en
Mendeliaanse randomisatie is e ...... epidemiologische onderzoeken.
@nl
label
Aleatorización mendeliana
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Mendeliaanse randomisatie
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Mendelian randomization
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Mendelsche Randomisierung
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Mendelsk randomisering
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Randomização mendeliana
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